发明名称 |
THERAPEUTIC AGENT FOR CORNEAL SENSORY NERVE DAMAGE CONTAINING SEMAPHORIN INHIBITOR AS ACTIVE INGREDIENT |
摘要 |
A compound represented by formula (1), or a pharmaceutically acceptable salt thereof is effective as a therapeutic agent or a prophylactic agent for a corneal disease or sensory nerve damage due to corneal surgery, and as a regeneration accelerator for corneal sensory nerves:
wherein R 1 represents a hydrogen atom or a carboxyl group, R 2 represents a hydrogen atom or a hydroxy group, R 3 represents a hydrogen atom or a carboxyl group, and R 4 represents a hydrogen atom or a hydroxy group. |
申请公布号 |
EP2679226(B1) |
申请公布日期 |
2016.04.06 |
申请号 |
EP20120749626 |
申请日期 |
2012.02.23 |
申请人 |
KEIO UNIVERSITY;SUMITOMO DAINIPPON PHARMA CO., LTD. |
发明人 |
OKANO, HIDEYUKI;TSUBOTA, KAZUO;SHIMMURA, SHIGETO;OMOTO, MASAHIRO;KISHINO, AKIYOSHI;MAEDA, MIHO |
分类号 |
A61K31/352;A61P27/02;A61P27/04;A61P43/00;C07D311/86 |
主分类号 |
A61K31/352 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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