| 发明名称 | MIPOL1-ETV1 gene rearrangements | ||
| 摘要 | Compositions and methods associated with recurrent MIPOL1-ETV1 genetic rearrangements that are useful for cancer diagnosis and therapy are disclosed. | ||
| 申请公布号 | US9303291(B2) | 申请公布日期 | 2016.04.05 |
| 申请号 | US200812667819 | 申请日期 | 2008.07.03 |
| 申请人 | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 发明人 | Chinnaiyan Arul M.;Tomlins Scott;Dhanasekaran Saravana Mohan |
| 分类号 | C12Q1/68 | 主分类号 | C12Q1/68 |
| 代理机构 | Casimir Jones S.C. | 代理人 | Casimir Jones S.C. ;Isenbarger Thomas;Casimir David |
| 主权项 | 1. A method for detecting a MIPOL1-ETV1 genetic rearrangement in a biological sample, the method comprising: a) contacting a biological sample with a probe directly labeled with a detectable label and comprising a sequence that hybridizes specifically to a junction at which an ETV1 gene is inserted into a MIPOL1 gene; and b) detecting the MIPOL1-ETV1 genetic rearrangement by detecting hybridization of said probe to a nucleic acid comprising said junction. | ||
| 地址 | Ann Arbor MI US | ||