| 摘要 |
The invention relates to a pharmaceutical product comprising a dibenzofuranone derivative as the active ingredient. The invention further relates to the use of dibenzofuranone derivatives to inhibit kinases, in particular serine/threonine kinases, to the use of dibenzofuranone derivatives for producing drugs and/or medicinal products for treatment, and to the use of dibenzofuranone derivatives as a diagnostic product for analyzing the role of protein kinases, in particular serine/threonine kinases, in particular protein kinase CK2 in cellular processes, the pathogenesis of diseases, ontogenesis and/or other developmental biological phenomena or relationships. |
| 主权项 |
1. A pharmaceutical composition, characterized in that it comprises, as an active ingredient, at least one compound with general formula I:wherein R1 is a substituted or unsubstituted aryl group or a substituted or unsubstituted alkyl group containing 1 to 16 C atoms, preferably a halogen, alkoxy and/or alkyl-substituted aryl group; R2, R3 and R5 are independently F, Cl, Br, I, H, a hydroxyl group or an alkoxy group containing 1 to 4 C atoms; and R4 is H, an alkyl or acyl group containing 1 to 16 C atoms, preferably (CnH2n+1)—CO, with n=1, 2, 3, 4, 5, 6, 7 or 8, pharmaceutically acceptable additives and/or auxiliary substances, and at least one further compound with an anti-neoplastic effect. |
