Method for attenuating immune response using mesenchymal stem cells and cytokines

摘要

The present invention relates to a composition and methods of treatment for inflammation comprising of adult stem cells and inflammatory cytokines. The invention further relates to the treatment of inflammation associated with autoimmune disorders, allergies, sepsis, cancer as well as to preventing, reducing or treating transplant rejection and/or graft-versus-host disease (GvHD).

主权项

1. A method for attenuating an immune response by suppressing the response of activated T-cells comprising administering an effective amount of
(a) isolated mesenchymal stem cells, (b) isolated interferon gamma, and (c) isolated interleukin-1 alpha, interleukin-1 beta or tumor necrosis factor alpha, to a subject in need of treatment thereby attenuating the subject's immune response.