发明名称 Aptamers that bind CD271
摘要 The invention generally relates to aptamers that bind CD271. In certain aspects, the invention provides an isolated nucleic acid ligand that binds to CD271, in which the nucleic acid ligand includes the nucleotide sequence of SEQ ID NO: 1 or the nucleotide sequence of SEQ ID NO: 2.
申请公布号 US9303263(B2) 申请公布日期 2016.04.05
申请号 US201414382681 申请日期 2014.02.28
申请人 VIVONICS, INC. 发明人 Gilman Vladimir Leo
分类号 A61K31/70;C07H21/02;C07H21/04;C12N15/115;A61L27/56;A61L27/54;A61L27/58;A61K31/711;C12N5/00;C12Q1/68 主分类号 A61K31/70
代理机构 Brown Rudnick LLP 代理人 Brown Rudnick LLP ;Meyers Thomas C.
主权项 1. An implantable medical product, the product comprising: a scaffold composed of a biocompatible material; and a plurality of nucleic acid ligands that binds to CD271, wherein the nucleic acid ligands comprise the nucleotide sequence of SEQ ID NO: 1 or the nucleotide sequence of SEQ ID NO: 2.
地址 Waltham MA US