Compositions comprising perivascular stem cells and nell-1 protein

摘要

Embodiments of the present invention provide a population of purified perivascular stem cells (PSC) or induced pluripotent stem cells (iPS) and a supernatant of stem cell free from the stem cell, a composition comprising any of these, and a method of using and making them.

主权项

1. A method of treating or ameliorating a medical condition, comprising
sorting a population of cells to obtain sorted perivascular stem cells identified by CD146, CD45, and CD34 antibodies as CD146−CD34+CD45− (adventitial cells) or CD146+CD34−CD45−(pericytes), and administering to a subject: the sorted adventitial cells or pericytes: or a composition comprising the sorted adventitial cells or pericytes; wherein the medical condition is associated with an injured or diseased tissue or organ, or wherein the medical condition is associated with a tissue or organ damaged by a disease or pathogen.