发明名称 Active principle for mitigating undesired medical conditions
摘要 A composition for treating or preventing inflammatory-related conditions includes as an active principle a carrier which exhibits a plurality of a scavenger structure capable of mitigating the activity of a mediator of inflammatory-related conditions. The scavenger structure includes a nucleophilic center complying with the formula X1(—R″—)(—R′)mHn where: a) X1 is a single-bonded heteroatom selected amongst N, O and S and exhibits a free electron pair; b) m is 0 or 1 and n is 1 or 2; c) —R″— is a bivalent organic group providing attachment to the carrier via one of its free valences and to X1 at the other free valence; and d) R′— is a monovalent organic group attached to the X1 via its free valence. A method for treating or preventing inflammatory-related conditions in an individual suffering from such conditions includes: providing the composition; and contacting the mediator within or separate from the individual.
申请公布号 US9302013(B2) 申请公布日期 2016.04.05
申请号 US201213982492 申请日期 2012.01.25
申请人 TERMIRA AB 发明人 Bowden Tim;Bergman Kristoffer;Engstrand Thomas;Soderberg Lennart
分类号 A61K47/48;A61K31/765;A61K31/785 主分类号 A61K47/48
代理机构 Young & Thompson 代理人 Young & Thompson
主权项 1. A composition for treating or preventing inflammatory-related conditions comprising an active principle (=AP) comprising a polyvinyl alcohol carrier which exhibits a plurality of a scavenger structure which is capable of mitigating and/or neutralising the activity of a mediator of inflammatory-related conditions, said scavenger structure comprising carbazate as a nucleophilic centre, said AP being attached to a support made of a material selected from the group consisting plastic, glass, metal, mineral, ceramic and polymeric material.
地址 Uppsala SE