发明名称 |
Active principle for mitigating undesired medical conditions |
摘要 |
A composition for treating or preventing inflammatory-related conditions includes as an active principle a carrier which exhibits a plurality of a scavenger structure capable of mitigating the activity of a mediator of inflammatory-related conditions. The scavenger structure includes a nucleophilic center complying with the formula X1(—R″—)(—R′)mHn where: a) X1 is a single-bonded heteroatom selected amongst N, O and S and exhibits a free electron pair; b) m is 0 or 1 and n is 1 or 2; c) —R″— is a bivalent organic group providing attachment to the carrier via one of its free valences and to X1 at the other free valence; and d) R′— is a monovalent organic group attached to the X1 via its free valence. A method for treating or preventing inflammatory-related conditions in an individual suffering from such conditions includes: providing the composition; and contacting the mediator within or separate from the individual. |
申请公布号 |
US9302013(B2) |
申请公布日期 |
2016.04.05 |
申请号 |
US201213982492 |
申请日期 |
2012.01.25 |
申请人 |
TERMIRA AB |
发明人 |
Bowden Tim;Bergman Kristoffer;Engstrand Thomas;Soderberg Lennart |
分类号 |
A61K47/48;A61K31/765;A61K31/785 |
主分类号 |
A61K47/48 |
代理机构 |
Young & Thompson |
代理人 |
Young & Thompson |
主权项 |
1. A composition for treating or preventing inflammatory-related conditions comprising an active principle (=AP) comprising a polyvinyl alcohol carrier which exhibits a plurality of a scavenger structure which is capable of mitigating and/or neutralising the activity of a mediator of inflammatory-related conditions, said scavenger structure comprising carbazate as a nucleophilic centre, said AP being attached to a support made of a material selected from the group consisting plastic, glass, metal, mineral, ceramic and polymeric material. |
地址 |
Uppsala SE |