发明名称 |
Haptens of quetiapine |
摘要 |
The invention relates to compounds of Formula I, wherein R1, R2, and R3 are defined in the specification, useful for the synthesis of novel conjugates and immunogens derived from quetiapine. The invention also relates to conjugates of a quetiapine hapten and a protein.; |
申请公布号 |
US9304126(B2) |
申请公布日期 |
2016.04.05 |
申请号 |
US201313970667 |
申请日期 |
2013.08.20 |
申请人 |
Janssen Pharmaceutica NV;Ortho-Clinical Diagnostics, Inc. |
发明人 |
Donahue Matthew Garrett;Gong Yong;Salter Rhys;Hryhorenko Eric;DeCory Thomas R.;Remmerie Bart;Sankaran Banumathi |
分类号 |
A61K31/554;C07D281/16;C07D417/04;G01N33/53;C07D417/12;C07D417/14;A61K47/48 |
主分类号 |
A61K31/554 |
代理机构 |
Johnson & Johnson |
代理人 |
Plantz Bernard F.;Johnson & Johnson |
主权项 |
1. The compound of Formula I wherein: R1 is H,CH2NH2, or CH2NHC(O)(CH2)mCO2H;
R2 is H,CH2NH2, or CH2NHC(O)(CH2)mCO2H;
R3 is H; provided that either R1 or R2 must be H, and further provided that both R1 and R2 may not be H simultaneously; m is 1, 2, 3, 4, or 5; and n is 1, 2, 3, 4, or 5. |
地址 |
Beerse BE |