Fluidically integrated rotary bead beader

摘要

A system for at least one of homogenization and lysis of a sample includes one or more walls forming an enclosed chamber having an inlet and a plurality of fluidic connections. A first fluidic network is coupled to at least one of the plurality of fluidic connections and a second fluidic network is coupled to at least one of the plurality of fluidic connections. The system further includes a rotary element within the chamber, and an actuator configured to rotate the rotary element. The first fluidic network is configured to introduce at least a sample into the chamber from at least one first reservoir. The second fluidic network is configured to expel at least the sample from the chamber to at least one second reservoir. The rotary element is rotated by the actuator about an axis extending along a length of the rotary element.

主权项

1. A system for at least one of homogenization and lysis of a sample, comprising:
a disposable housing configured to be removably coupled to an analyzer, the disposable housing comprising:
a first reservoir;a second reservoir;one or more walls forming an enclosed chamber having an inlet and a plurality of fluidic connections, wherein at least one of the one or more walls of the enclosed chamber comprise a thermally controllable surface;a first fluidic network coupled to at least one of the plurality of fluidic connections and configured to introduce at least the sample to the enclosed chamber from the first reservoir;a second fluidic network coupled to at least one of the plurality of fluidic connections and configured to expel at least the sample from the enclosed chamber to the second reservoir; anda rotary element disposed within the enclosed chamber.