| 发明名称 |
Substituted biaryl derivatives and methods of use thereof |
| 摘要 |
The present invention relates to Substituted Biaryl Derivatives, compositions comprising a Substituted Biaryl Derivative, and methods of using the Substituted Biaryl Derivatives for treating or preventing obesity, diabetes, a metabolic disorder, a cardiovascular disease or a disorder related to the activity of GPR119 in a patient. |
| 申请公布号 |
US9301929(B2) |
申请公布日期 |
2016.04.05 |
| 申请号 |
US201013505819 |
申请日期 |
2010.11.16 |
| 申请人 |
Merck Sharp & Dohme Corp. |
发明人 |
Boyle Craig D.;Lankin Claire M.;Greenlee William J.;Harris Joel M. |
| 分类号 |
C07D491/08;A61K31/00;C07D451/02 |
主分类号 |
C07D491/08 |
| 代理机构 |
|
代理人 |
Cocuzzo Anna L.;Fitch Catherine D. |
| 主权项 |
1. A compound having the formula:or a pharmaceutically acceptable salt thereof, wherein E is: each occurrence of R6 is a ring carbon atom substituent and is independently selected from halo, —CF3, —OH, alkyl, C3-C7cycloalkyl and —O—alkyl; R15 is alkyl; and m is 0 or 1. |
| 地址 |
Rahway NJ US |
