发明名称 COUMARIN DERIVATIVES AND METHODS OF USE IN TREATING HYPERPROLIFERATIVE DISEASES.
摘要 Coumarin derivative compounds and methods for the treatment of hyperproliferative diseases, such as cancer, polycystic kidney disease, and fibrosis of different tissues (e.g., idiopathic pulmonary fibrosis), are provided. The methods include administering to a subject a compound as described herein. Also provided are methods for inhibiting the interaction between two or more heat shock protein chaperones in a cell.
申请公布号 MX2015013175(A) 申请公布日期 2016.04.04
申请号 MX20150013175 申请日期 2014.03.14
申请人 DISCOVERYBIOMED, INC. 发明人 ERIK SCHWIEBERT;JOHN STREIFF;JOHN DIXON;HONGWU GAO;JOSEPH P. RITCHIE;ERIC C. SEALES;DEBORAH MAI
分类号 C07D417/04;A61K31/4196;A61K31/422;A61K31/4245;A61K31/427;A61K31/433;A61K31/4427;A61K31/519;A61K31/5377;A61P35/00;C07D405/04;C07D413/04;C07D413/14;C07D471/04;C07D491/052;C07D493/04 主分类号 C07D417/04
代理机构 代理人
主权项
地址