摘要 |
PROBLEM TO BE SOLVED: To provide a method for efficiently manufacturing a compound having a N-acyl carbamoyl group and a ring containing a lactone skeleton.SOLUTION: There is provided a method of converting to N-acyl carbamoyl group-containing lactone compound represented by the formula (4) by reacting carboxylic aid or a reactive derivative thereof with a cyano group-containing lactone compound. In the formula, Ris a halogen atom, an alkyl group which has 1 to 6 carbon atoms and may have a halogen atom or the like, A is an alkylene group having 1 to 6 carbon atoms, an oxygen atom, a sulfur atom or non-binding, m is an integer of 0 to 8, X is a specific N-acyl carbamoyl group and n is an integer of 1 to 9.SELECTED DRAWING: None |