发明名称 |
SUBSTITUTED PHENYLAZOLE DERIVATIVE |
摘要 |
Compounds are provided having an excellent hypoglycemic effect and β cell- or pancreas-protecting effects, or pharmaceutically acceptable salts thereof, and a pharmaceutical composition having an excellent therapeutic effect and/or prophylactic effect on type 1 diabetes, type 2 diabetes, and the like, which cause hyperglycemia due to abnormal glucose metabolism. A compound represented by general formula (I), or a pharmaceutically acceptable salt thereof, is disclosed.; |
申请公布号 |
US2016090375(A1) |
申请公布日期 |
2016.03.31 |
申请号 |
US201514956240 |
申请日期 |
2015.12.01 |
申请人 |
DAIICHI SANKYO COMPANY, LIMITED |
发明人 |
YAMANOI Shigeo;NAMIKI Hidenori;OCHIAI Yuichi;HOSHINO Madoka;MATSUMOTO Koji |
分类号 |
C07D403/12;C07D249/06;C07D401/14;C07D401/12 |
主分类号 |
C07D403/12 |
代理机构 |
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代理人 |
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主权项 |
1. A compound of formula (IV): or a pharmaceutically acceptable salt thereof, wherein X is CH or N, R1 is —C(═O)—NH—R5, —NH—C(═O)—NH—R5, or —S(═O)2—R5, R3 is —CH3 or —C2H5, and R5 is —H, a C1-C6 alkyl group, a C3-C6 cycloalkyl group, oreach of which may be substituted with 1 to 3 —OH. |
地址 |
Tokyo JP |