| 发明名称 |
SYNTHESIS OF A NEUROSTIMULATIVE PIPERAZINE |
| 摘要 |
The invention describes an improved synthesis for piperazine derivatized with nicotinic acid and a benzyl moiety. The product compounds are useful for treatment of neurological conditions. |
| 申请公布号 |
US2016090358(A1) |
申请公布日期 |
2016.03.31 |
| 申请号 |
US201514964397 |
申请日期 |
2015.12.09 |
| 申请人 |
NEURALSTEM, INC. |
发明人 |
VENKATRAMAN Sripathy;MAHMOOD Syed;MOBELE Bingidimi I.;LAPINA Olga;VERCOE Kellie;LI Ying;SALSBURY Jonathan;MCLAWS Mark |
| 分类号 |
C07D213/74 |
主分类号 |
C07D213/74 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method to convert a compound of formula (1): to a phosphate salt by reacting said compound with phosphoric acid wherein the reaction occurs in a solvent mixture consisting of ethanol and water. |
| 地址 |
Germantown MD US |
