发明名称 METHOD FOR PRODUCING POLYGUANIDINES
摘要 The invention relates to a method for producing polycondensation products of guanidine, aminoguanidine or diaminoguanidine G with one or more benzyl- or allyl-derivatives BA according to the following reaction scheme: wherein X represents, respectively independently, a leaving group; each R1 represents independently either an aromatic ring system with at least one aromatic ring, which optionally contains one or more heteroatoms selected from 0, N and S and which is optionally substituted with one or two vinyl groups, to which the group(s) -CH2-X is/are bound, or represents ethylene; Gua represents a guanidindiyl-, aminoguanidindiyl- or Ddaminoguanidindiyl-group; Y represent H-Gua and Z represents H; or Y and Z together represent a chemical bond in order to produce a cyclic structure; wherein at least one benzyl- or allyl-derivative BA is subjected to a polycondensation reaction with an excess of guanidine, aminoguanidine or diaminoguanidine G with the elimination of HX.
申请公布号 WO2016015081(A9) 申请公布日期 2016.03.31
申请号 WO2015AT50187 申请日期 2015.07.30
申请人 SEALIFE PHARMA GMBH 发明人 PRETSCH, ALEXANDER
分类号 C07C277/08;A61K31/155;C07C279/04 主分类号 C07C277/08
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