| 摘要 |
THE PRESENT INVENTION DISCLOSES A PROCESS FOR THE PREPARATION OF SUCCINIC ACID COMPRISING THE STEPS OF: A) PROVIDING AN AQUEOUS MEDIUM COMPRISING MAGNESIUM SUCCINATE BY FERMENTATION, WHEREIN A CARBOHYDRATE SOURCE IS FERMENTED BY MEANS OF A MICRO-ORGANISM TO FORM SUCCINIC ACID, A MAGNESIUM BASE BEING ADDED AS NEUTRALISING AGENT DURING FERMENTATION TO PROVIDE THE MAGNESIUM SUCCINATE; B) SUBJECTING THE AQUEOUS MEDIUM COMPRISING MAGNESIUM SUCCINATE TO A CRYSTALLISATION STEP AND A SALT EXCHANGE STEP TO PROVIDE AN AQUEOUS SOLUTION COMPRISING A MONOVALENT SUCCINATE SALT, WHEREIN THE SALT EXCHANGE, WHICH IS PERFORMED EITHER PRIOR TO OR AFTER CRYSTALLISATION, COMPRISES TREATING THE MAGNESIUM SUCCINATE WITH A MONOVALENT BASE TO PROVIDE A MAGNESIUM BASE AND THE MONOVALENT SUCCINATE SALT; C) ADJUSTING THE CONCENTRATION OF THE MONOVALENT SUCCINATE SALT IN THE AQUEOUS SOLUTION TO A VALUE BETWEEN 10 AND 35 WT.%; D) SUBJECTING THE AQUEOUS SOLUTION COMPRISING THE MONOVALENT SUCCINATE SALT TO WATER-SPLITTING ELECTRODIALYSIS, TO PRODUCE A FIRST SOLUTION COMPRISING MONOVALENT BASE AND A SECOND SOLUTION COMPRISING SUCCINIC ACID AND MONOVALENT SUCCINATE SALT, THE ELECTRODIALYSIS BEING CARRIED OUT TO A PARTIAL CONVERSION OF 40 TO 95 MOLE%; E) SEPARATING THE SECOND SOLUTION COMPRISING SUCCINIC ACID AND MONOVALENT SUCCINATE SALT INTO SUCCINIC ACID AND A SOLUTION COMPRISING THE MONOVALENT SUCCINATE SALT BY CRYSTALLISATION; F) RECYCLING THE SOLUTION OF STEP E) COMPRISING THE MONOVALENT SUCCINATE SALT TO STEP D). |
