发明名称 |
USES OF TREHALOSE IN CELL SUSPENSIONS |
摘要 |
Disclosed are cellular compositions and methods relating to the use of aqueous trehalose media to suspend cells. A trehalose-containing medium can be used to inhibit cellular clumping, for example upon dilution of more concentrated cellular preparations into the trehalose-containing medium. In certain embodiments cells, after cryopreservation and thawing, are combined with a trehalose-containing medium to prepare a clumping-inhibited cell suspension. |
申请公布号 |
US2016089401(A1) |
申请公布日期 |
2016.03.31 |
申请号 |
US201514869006 |
申请日期 |
2015.09.29 |
申请人 |
Cook General Biotechnology LLC |
发明人 |
Woods Erik John;Thirumala Sreedhar;Zacharias Shelly J.;Welty Matthew B. |
分类号 |
A61K35/28;A61K47/26 |
主分类号 |
A61K35/28 |
代理机构 |
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代理人 |
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主权项 |
1. A method for preparing a cellular composition, comprising:
(a) thawing cryopreserved cells to provide thawed, viable cells; and (b) combining the thawed, viable cells with an aqueous medium containing trehalose to provide a trehalose-containing cell suspension. |
地址 |
Indianapolis IN US |