| 发明名称 |
STABILITY OF PROGESTOGEN FORMULATIONS |
| 摘要 |
In a preparation for hormone replacement therapy having a low content of progestogen, the stability of the progestogen component can be enhanced by using a cellulosic binder, for example hydroxypropylcellulose, in stead of a non-cellulosic binder. |
| 申请公布号 |
US2016089381(A1) |
申请公布日期 |
2016.03.31 |
| 申请号 |
US201514964645 |
申请日期 |
2015.12.10 |
| 申请人 |
Novo Nordisk HealthCare AG |
发明人 |
Nielsen Vibeke Friis |
| 分类号 |
A61K31/57;A61K9/20;A61K9/28;A61K31/565 |
主分类号 |
A61K31/57 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A pharmaceutical formulation comprising (i) a progestogen and (ii) a cellulosic binder, having a content of NETA in the range from about 0.05 to about 1.5% (w/w) relative to the total formulation or an equivalent amount of a non-NETA progestogen. |
| 地址 |
Zurich CH |
