发明名称 STABLE EYE DROPS FOR HEALING CORNEAL DISORDERS
摘要 The purpose of this invention is to maximize the efficacy of, minimize the incidence of adverse effects from, and improve the storage stability of eye drops that contain a peptide (SSSR), the amino acid sequence of which is represented by Ser-Ser-Ser-Arg, or a pharmaceutically acceptable salt thereof, and a peptide (FGLM), the amino acid sequence of which is represented by Phe-Gly-Leu-Met-NH, or a pharmaceutically acceptable salt thereof. The concentration ratio between the SSSR or a pharmaceutically acceptable salt thereof and the FGLM or a pharmaceutically acceptable salt thereof is between 1/15 and 1/50. The concentration of the SSSR or a pharmaceutically acceptable salt thereof is between 0.001% and 0.3% (w/v), and the concentration of the FGLM or a pharmaceutically acceptable salt thereof is between 0.015% and 1.5% (w/v). The pH of the eye drops is maintained between 2.5 and 6.5.
申请公布号 EA022927(B1) 申请公布日期 2016.03.31
申请号 EA20120000533 申请日期 2010.09.24
申请人 SANTEN PHARMACEUTICAL CO., LTD. 发明人 NAKAMURA Takahiro;NAKADA Yuichiro;NAGANO Takashi;NAKAMURA Masatsugu
分类号 A61K38/27;A61K9/08;A61K47/02;A61K47/04;A61P27/02 主分类号 A61K38/27
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