发明名称 |
TREATMENT OF RESPIRATORY CONDITIONS WITH NOTCH INHIBITORS |
摘要 |
The present invention relates to methods of treating or preventing respiratory infections, in particular respiratory infections in patients with an underlying respiratory disorder such as chronic obstructive pulmonary disease (COPD). The present invention also relates to methods of treating or preventing COPD or COPD exacerbations. The invention particularly describes the role of Notch 3 and/or Notch 4 signalling in such methods and the use of Notch 3 and/or Notch 4 as therapeutic and screening targets. |
申请公布号 |
WO2016046151(A1) |
申请公布日期 |
2016.03.31 |
申请号 |
WO2015EP71638 |
申请日期 |
2015.09.22 |
申请人 |
GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENTLIMITED |
发明人 |
BEINKE, SOREN;BELYAEV, NIKOLAI NIKOLAEVICH;HESSEL, EDITH |
分类号 |
A61K39/395;A61K31/00;A61K31/5513 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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