| 发明名称 |
Spiro-oxindole MDM2 antagonists |
| 摘要 |
Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as therapeutics for the treatment of cancer and other diseases. |
| 申请公布号 |
AU2012253339(B2) |
申请公布日期 |
2016.03.31 |
| 申请号 |
AU20120253339 |
申请日期 |
2012.05.11 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN;SANOFI |
发明人 |
WANG, SHAOMENG;SUN, WEI;AGUILAR, ANGELO;GARCIA-ECHEVERRIA, CARLOS |
| 分类号 |
C07D487/10;A61K31/407;A61P35/00;C07D413/12 |
主分类号 |
C07D487/10 |
| 代理机构 |
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