| 摘要 |
Provided are methods, compositions, and systems for the detection, diagnosis, prediction, prognosis, and staging of viruses, such as human papilloma virus (HPV) and viral nucleic acids and associated diseases and conditions such as cancer, in subjects and biological samples derived therefrom. In some aspects, the methods detect and/or discern between forms of viruses, such as free, episomal, and integrated forms and provide prognostic and predictive information about the diseases or conditions. Among the viruses are human papilloma viruses (HPV), Epstein Barr virus (EBV), and poxviruses. Among the diseases and conditions are neoplastic, cancerous, pre- malignant, and proliferative diseases, disorders, and conditions. |
