| 摘要 |
The invention relates to a compound of the structural formula;;or a hydrate or an isotope thereof. The invention also relates to a preparation method thereof and methods of providing dietary organoselenium, inactivating an enzyme, modulating the activity of a protein (e.g., methyltransferase) or nucleic acid, identifying a methyltransferase that reacts with compound, and oxidizing a methyltransferase-reactive substrate. |
| 主权项 |
1. A compound having a structural formula: or a hydrate or an isotope thereof, wherein
R1 is COOH, NH2, CH2OH, CHO, CONH2, Cl, Br, I, H, O, OH, N3, CH3 or CN;R2 is NH2, COOH, CH2OH, CHO, CONH2, Cl, Br, I, H, O, OH, N3, CH3 or CN;R3 is H or a linear or branched C1-C4 alkyl;R4 is H or a linear or branched C1-C4 alkyl;R5 is CH2, —CH(CH3), C(CH3)2 or C2H4;R6 is OH, O or a linear or branched C1-C4 alkoxy;R7 is OH, O or a linear or branched C1-C4 alkoxy;R8 is NH2, COOH, Cl, Br, I, H, O, OH, N3, CH3 or CN; andR9 is O, N, S or CH2. |
