发明名称 Pharmaceutical compositions of 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-((trans)-4-methoxycyclohexyl)-3,4-dihydropyrazino [2,3-b]pyrazin-2(1h)-one, a solid form thereof and methods of their use
摘要 Disclosed herein are compositions of 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-((trans)-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one, solid forms, isotopologues and metabolites thereof, stearic acid and lactose monohydrate and methods of their use for the treatment of a disease disorder, or condition such as cancer, especially solid tumours, non-Hodgkin lymphoma and glioblastoma multiforme, an inflammatory condition, an immunological condition, a neurodegenerative disease, diabetes, obesity, a neurological disorder, an age-related disease, or a cardiovascular condition.
申请公布号 NZ625511(A) 申请公布日期 2016.03.31
申请号 NZ20120625511 申请日期 2012.11.30
申请人 SIGNAL PHARMACEUTICALS LLC 发明人 XU JEAN;CONNOLLY TERRENCE JOSEPH;KLOPFER KEVIN JOSEPH;LEONG WILLIAM WEI-HWA;MENON ANIL;MIKLOS AMANDA NICOLE;COHEN BENJAMIN;LEE THOMAS;BOERSEN NATHAN;KREILEIN MATTHEW MICHAEL;LI YING;HUI HO-WAH;GAMBOA JUAN ANTONIO
分类号 A61K9/00;A61K9/20;A61K9/28;A61K31/4985;A61P35/00;C07D487/04 主分类号 A61K9/00
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