摘要 |
Disclosed herein are compositions of 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-((trans)-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one, solid forms, isotopologues and metabolites thereof, stearic acid and lactose monohydrate and methods of their use for the treatment of a disease disorder, or condition such as cancer, especially solid tumours, non-Hodgkin lymphoma and glioblastoma multiforme, an inflammatory condition, an immunological condition, a neurodegenerative disease, diabetes, obesity, a neurological disorder, an age-related disease, or a cardiovascular condition. |