METHYL-AND TRIFLUOROMETHYL-SUBSTITUTED PYRROLOPYRIDINE MODULATORS OF RORC2 AND METHODS OF USE THEREOF
摘要
The present invention provides methyl-and trifluoromethyl-substituted pyrrolopyridines, pharmaceutical compositions thereof, methods of modulating RORγ activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such pyrrolopyridines and pharmaceutical compositions thereof.
申请公布号
WO2016046755(A1)
申请公布日期
2016.03.31
申请号
WO2015IB57314
申请日期
2015.09.22
申请人
PFIZER INC.
发明人
FLICK, ANDREW CHRISTOPHER;JONES, PETER;KAILA, NEELU;MENTE, SCOT RICHARD;SCHNUTE, MARK EDWARD;TRZUPEK, JOHN DAVID;VAZQUEZ, MICHAEL L.;XING, LI;ZHANG, LIYING;WENNERSTÅL, GÖRAN MATTIAS;ZAMARATSKI, EDOUARD
