发明名称 Optically active pde10 inhibitor
摘要 Disclosed herein is (S)-1-(5-(4-chloro-3,5-dimethoxyphenyl)furan-2-yl)-2-ethoxy-2-(4-(5-methyl-1,3,4-thiadiazol-2-yl)phenyl)ethanone. Also disclosed are crystal forms of (S)-1-(5-(4-chloro-3,5-dimethoxyphenyl)furan-2-yl)-2-ethoxy-2-(4-(5-methyl-1,3,4-thiadiazol-2-yl)phenyl)ethanone, pharmaceutical compositiona of the compound, processes for its synthesis and the use of the compound for inhibiting PDE10 and treatment of neurological disorders such as schizophrenia and post-traumatic stress disorder.
申请公布号 NZ630803(A) 申请公布日期 2016.03.31
申请号 NZ20140630803 申请日期 2014.09.10
申请人 OMEROS CORPORATION 发明人 ZUTA CHARLES PRINCE;FERGUSON KENNETH M;CUTSHALL NEIL S
分类号 A61K31/433;A61K31/341;C07D285/12;C07D307/46 主分类号 A61K31/433
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