CHLOROGENIC ACID LYOPHILISED POWDER FOR INJECTION HAVING HIGH RESOLUBILITY AND HIGH STABILITY

摘要

A chlorogenic acid lyophilised powder for injection and a preparation method therefor. The chlorogenic acid lyophilised powder for injection is prepared from raw materials having the following weight ratio: 30 parts chlorogenic acid, 60-90 parts mannitol and 1-3 parts sodium bisulphite. The crystalline form of the chlorogenic acid is an orthorhombic crystal system, the space group is P212121, the cell parameters are a = 7.7291 (2) Å, b = 10.9808 (2) Å and c = 36.5334 (7) Å, α = β = γ = 90°, Z = 8, and the cell volume is 3100.65 (11) Å3.