HIGH AFFINITY HUMAN ANTIBODIES TO HUMAN ANGIOPOIETIN-2

摘要

THE PRESENT INVENTION PROVIDES ANTIBODIES THAT BIND TO ANGIOPOIETINE2 (ANG-2) AND METHODS OF USING SAME. ACCORDING TO CERTAIN EMBODIMENTS OF THE INVENTION, THE ANTIBODIES ARE FULLY HUMAN ANTIBODIES THAT BIND TO HUMAN ANG-2. THE ANTIBODIES OF THE INVENTION ARE USEFUL, INTER ALIA, FOR THE TREATMENT OF DISEASES AND DISORDERS ASSOCIATED WITH ONE OR MORE ANG-2 BIOLOGICAL ACTIVITIES INCLUDING ANGIOGENESIS.