METHODS AND COMPOSITIONS FOR INDUCING PROTECTIVE IMMUNITY AGAINST HUMAN IMMUNODEFICIENCY VIRUS INFECTION
摘要
Compositions, vaccines and methods for inducing protective immunity against Human Immunodeficiency Virus (HIV) infection are described. Heterologous vaccine combinations of one or more viral expression vectors and an isolated antigenic polypeptide induced strong protective immunity against infections by one or multiple clades of HIV.
申请公布号
WO2016049287(A1)
申请公布日期
2016.03.31
申请号
WO2015US51891
申请日期
2015.09.24
申请人
BETH ISRAEL DEACONESS MEDICAL CENTER, INC.;CRUCELL HOLLAND B.V.
发明人
BAROUCH, DAN;SCHUITEMAKER, JOHANNA;PAU, MARIA GRAZIA;VAN MANEN, DANIELLE;TOMAKA, FRANK;HENDRIKS, JENNIFER, ANNE