| 发明名称 |
OPTICALLY ACTIVE DIBENZYLAMINE DERIVATIVE, AND MANUFACTURING METHOD FOR SAME. |
| 摘要 |
A substantially optically-pure (S)-trans-{4-[({2-[({1-[3,5-bis(trifluoromethyl) phenyl] ethyl}{5-[2-(methylsulfonyl) ethoxy] pyrimidine-2-yl} amino) methyl]-4-(trifluoromethyl) phenyl} (ethyl) amino) methyl] cyclohexyl} aceitic acid having the effect of reducing the amount of PCSK9 proteins and increasing the amount of LDL receptors, or a salt thereof, or a solvate thereof. |
| 申请公布号 |
MX338024(B) |
申请公布日期 |
2016.03.31 |
| 申请号 |
MX20120014149 |
申请日期 |
2011.06.03 |
| 申请人 |
KOWA COMPANY, LTD. |
发明人 |
TADAAKI OHGIYA;KOICHI YAMAZAKI;KATSUTOSHI MIYOSAWA;TAKESHI MURAKAMI;KIMIYUKI SHIBUYA;TAICHI KUSAKABE |
| 分类号 |
C07D239/47;A61K31/505;A61P3/06;A61P9/10;A61P13/08;A61P13/12;A61P17/06;A61P19/10;A61P25/28;A61P27/02;A61P29/00;A61P31/12;A61P33/00;A61P35/00;A61P43/00 |
主分类号 |
C07D239/47 |
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