NOVEL GABAA AGONISTS AND METHODS OF USING TO CONTROL AIRWAY HYPERRESPONSIVENESS AND INFLAMMATION IN ASTHMA
摘要
Novel methods of treating inflammation and airway constriction using GABAergic compounds with reduced benzo-diazepine-like CNS activity are provided. Novel compounds which selectively target alpha-4 and alpha-5 GABAA receptors and methods of using those compounds to treat bronchoconstriction and inflammation are provided herein.
申请公布号
EP2897963(A4)
申请公布日期
2016.03.30
申请号
EP20130838190
申请日期
2013.09.20
申请人
UWM RESEARCH FOUNDATION, INC.;THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
