The present invention relates to a method of labelling biological molecules with 18F, via attachment to fluorine to a macrocyclic metal complex of a non-radioactive metal, where the metal complex is conjugated to the biological molecule. Also provided are pharmaceutical compositions, kits and methods of in vivo imaging.
申请公布号
EP2806901(B1)
申请公布日期
2016.03.30
申请号
EP20130701070
申请日期
2013.01.22
申请人
GE HEALTHCARE UK LIMITED;UNIVERSITY OF SOUTHAMPTON
发明人
BHALLA, RAJIV;LUTHRA, SAJINDER, KAUR;REID, GILL;LEVASON, WILLIAM