| 发明名称 |
NOVEL IMIDAZOLE-SUBSTITUTED ARYLAMIDES |
| 摘要 |
Compounds of the formula I: wherein R1 is optionally substituted imidazolyl, and R2, R3, R4, R5, R6, R7 and R8 are as defined herein. Also provided are methods of using the compounds for treating diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist and methods of making the subject compounds. |
| 申请公布号 |
EP2234981(B1) |
申请公布日期 |
2016.03.30 |
| 申请号 |
EP20080862496 |
申请日期 |
2008.12.08 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
CHEN, LI;DILLON, MICHAEL PATRICK;FENG, LICHUN;HAWLEY, RONALD CHARLES;YANG, MINMIN |
| 分类号 |
C07D233/64;A61K31/33;A61P25/06;C07D401/14;C07D403/12 |
主分类号 |
C07D233/64 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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