Vaccine against smallpox

摘要

In the present invention, there is disclosed a pharmaceutical composition containing a clonal strain of attenuated vaccinia virus that is isolated from cultured cells in which ACAM1000 (ATCC Deposit No. PTA-3321) or a progenic virus thereof has been cultured. The pharmaceutical composition of the present invention is suitable for the use as a vaccine in prevention methods or treatment of patients being attacked by the vaccinia virus. The invention further discloses a process for preparing such vaccines.