| 发明名称 | Stabilized calcium phosphate complexes | ||
| 摘要 | The present invention relates to a phosphopeptide-stabilized amorphous calcium phosphate and/or amorphous calcium fluoride phosphate complex, wherein the complex is formed at a pH of below 7.0. Methods of making such complexes are also provided. The complexes are useful in dental applications, in particular in dental remineralisation. | ||
| 申请公布号 | US9295628(B2) | 申请公布日期 | 2016.03.29 |
| 申请号 | US201314077713 | 申请日期 | 2013.11.12 |
| 申请人 | The University of Melbourne | 发明人 | Reynolds Eric Charles |
| 分类号 | A61K8/21;A61K8/64;A61K8/20;A61K8/24;A61Q11/00;C07K7/06;A61K8/69;A61K38/00 | 主分类号 | A61K8/21 |
| 代理机构 | Merchant & Gould P.C. | 代理人 | Merchant & Gould P.C. |
| 主权项 | 1. A composition for dental restoration comprising a phosphopeptide stabilised amorphous calcium phosphate (ACP) or amorphous calcium fluoride phosphate (ACFP) complex, wherein the complex is formed at a pH of from about 5.0 up to but below 7.0, and wherein the ACP or ACFP complex has bound and unbound calcium, wherein the bound calcium in the complex is less than the bound calcium in an ACP or ACFP complex formed at a pH of 7.0 and the ACP or ACFP is predominantly in a basic form. | ||
| 地址 | Parkville, Victoria AU | ||