| 发明名称 | Method for purifying a pyrazolinone derivative | ||
| 摘要 | A method for purifying a pyrazolinone derivative comprising a step of mixing a solution containing a mixture containing the pyrazolinone derivative and a good solvent which can dissolve the pyrazolinone derivative with a poor solvent to crystallize the pyrazolinone derivative. | ||
| 申请公布号 | US9296700(B2) | 申请公布日期 | 2016.03.29 |
| 申请号 | US201013320281 | 申请日期 | 2010.06.01 |
| 申请人 | Sumitomo Chemical Company, Limited | 发明人 | Hatano Ryo;Miyaoka Sosuke;Abe Shinsuke |
| 分类号 | C07D231/52 | 主分类号 | C07D231/52 |
| 代理机构 | Panitch Schwarze Belisario & Nadel LLP | 代理人 | Panitch Schwarze Belisario & Nadel LLP |
| 主权项 | 1. A method for purifying a pyrazolinone compound, wherein the pyrazolinone compound is 1-[(2-propenylthio)carbonyl]-2-(1-methylethyl)-4-(2-methylphenyl)-5-amino-1H-pyrazol-3-one, comprising a step of adding a solution containing a mixture containing the pyrazolinone compound and a good solvent which can dissolve the pyrazolinone derivative to a poor solvent and crystallizing the pyrazolinone compound at −20° C. to 20° C., wherein the good solvent is xylene, and the poor solvent is hexane, and wherein 1 to 50 parts by weight of the pyrazolinone compound is added per 100 parts by weight of the poor solvent. | ||
| 地址 | Tokyo JP | ||