发明名称 |
Absorbable poly (p-dioxanone-co-glycolide) monofilament fibers possessing mid-term strength retention post-implantation |
摘要 |
Novel absorbable monofilament sutures and fibers having unique and improved properties are disclosed including mid-term strength retention post-implantation. Also disclosed is a novel method of manufacturing absorbable monofilament sutures and fibers. The sutures and fibers are extruded from poly(p-dioxanone-co-glycolide) copolymers. |
申请公布号 |
US9296145(B2) |
申请公布日期 |
2016.03.29 |
申请号 |
US201314068226 |
申请日期 |
2013.10.31 |
申请人 |
Ethicon, Inc. |
发明人 |
Andjelic Sasa;Keilman Kenneth;Jamiolkowski Dennis D. |
分类号 |
A61B17/04;B29C47/00;D01D5/098;A61B17/06;A61L17/12;B29C47/86;B29C47/88;B29K73/00;B29L31/00 |
主分类号 |
A61B17/04 |
代理机构 |
|
代理人 |
Skula E. Richard |
主权项 |
1. An absorbable monofilament suture, comprising:
a poly(p-dioxanone-co-glycolide) copolymer, wherein the mole percent of polymerized p-dioxanone is from about 90 to about 94, the mole percent of polymerized glycolide is from about 6 mole percent to about 10 mole percent, the copolymer made utilizing a monofunctional polymerization initiator and a difunctional polymerization initiator at a mole ratio of monofunctional initiator to difunctional initiator of from about 40/60 to about 60/40, wherein said suture has a straight tensile strength of at least 80 Kpsi, a Young's Modulus of less than 200 Kpsi, and a breaking strength retention (BSR) of at least 50% at 3 weeks post-implantation and at least 30% at 4 weeks post-implantation. |
地址 |
Somerville NJ US |