发明名称 Biomaterial construct, its producing method, biomaterial support, target material purifying method, affinity chromatography container, separation chip, analyzing method and analyzing separator for target material, biomaterial complex, and its support, sensor chip, solid support with biomaterial fixed thereon
摘要 A biomaterial structure containing a larger amount of biomaterial than the conventional art with maintaining the reactivity of the biomaterial is provided by linking particulate lumps in which the biomaterial is bound with a compound capable of binding to the biomaterial, wherein the particle diameter of the particulate lumps is 10 μm or smaller.
申请公布号 US9297800(B2) 申请公布日期 2016.03.29
申请号 US201113239985 申请日期 2011.09.22
申请人 Mitsubishi Chemical Corporation;LSI Medience Corporation 发明人 Isojima Tatsushi;Tanaka Hiroyuki;Shiroya Toshifumi;Takeuchi Hisao;Hanasaki Minako;Ifuku Yasuo
分类号 G01N33/543 主分类号 G01N33/543
代理机构 Oblon, McClelland, Maier & Neustadt, L.L.P. 代理人 Oblon, McClelland, Maier & Neustadt, L.L.P.
主权项 1. A biomaterial-immobilized solid-state carrier, comprising: a solid-state carrier; and a matrix formed on a surface of the carrier, the matrix including a support material, a bio-related material, and a compound capable of binding to the bio-related material and/or the support material; wherein the compound is a polymer compound; the compound has two or more binding functional groups capable of binding to the biorelated material and/or the support material through covalent binding as reactive group in each molecule; the matrix comprises a structure having a core of the support material and having a principal chain comprising the bio-related material and the compound, and a cross-linked structure between the compound and the bio-related material and/or the compound and the support material through the binding functional group; and the matrix at least partially contains a cross-linked structure in which the biorelated material is positioned between the compounds by binding the bio-related material to the compounds through the two or more binding functional groups.
地址 Tokyo JP