| 发明名称 | Pharmaceutical composition for preventing or treating diabetes or fatty liver containing a CYP4A inhibitor as an active ingredient | ||
| 摘要 | The present invention relates to a pharmaceutical composition for preventing or treating diabetes or fatty liver, and more specifically relates to a pharmaceutical composition for preventing or treating diabetes or fatty liver containing a CYP4A (cytochrome P450A) inhibitor as an active ingredient. According to the present invention, the CYP4A inhibitor suppresses endoplasmic reticulum stress, reduces the blood insulin concentration and suppresses apoptosis of liver cells, and hence exhibits effects in preventing or treating diabetes or fatty liver. | ||
| 申请公布号 | US9295667(B2) | 申请公布日期 | 2016.03.29 |
| 申请号 | US201414178090 | 申请日期 | 2014.02.11 |
| 申请人 | Korea Basic Science Institute | 发明人 | Kim Gun-Hwa;Kim Soohyun;Choi Jong-Soon;Kim Seung Il;Park Edmond Changkyun |
| 分类号 | A61K31/41;A61K31/415;A61K31/20;A61K31/18;A61K31/15;A61K31/4192;A61K31/155;A61K31/201;A61K31/4174 | 主分类号 | A61K31/41 |
| 代理机构 | Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. | 代理人 | Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. ;Kim Kongsik;Emmons Richard B. |
| 主权项 | 1. A method for treating diabetes or fatty liver, comprising administering to a subject in need thereof an effective amount of a cytochrome P450 4A (CYP4A) inhibitor. | ||
| 地址 | Daejeon KR | ||