发明名称 |
biomateriais de fosfato de cálcio com gálio |
摘要 |
The present invention relates to a galliated calcium-phosphate biomaterial comprising a gallium-doped phosphocalcic compound of formula (I):
€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒCa (10.5-1.5x) Ga x (PO 4 ) 7 €ƒ€ƒ€ƒ€ƒ€ƒ(I)
wherein 0 < x < 1 and the salts, hydrates and mixtures thereof and/or a calcium deficient apatite structure with in particular a (Ca + Ga)/P molar ratio in the range of 1.3 to 1.67, and a gallium content up to 4.5 % by weight. It also relates to processes of preparation of such materials and uses thereof, in particular as dental or bony implants. It further relates to a kit comprising a galliated calcium-phosphate biomaterial in combination with a fluid component. It finally relates to methods of use of the galliated calcium-phosphate biomaterial, notably for III) ions increase radio-opacity after bone implantation and can be released for inhibiting bone resorption. |
申请公布号 |
BRPI1006730(A2) |
申请公布日期 |
2016.03.29 |
申请号 |
BR2010PI06730 |
申请日期 |
2010.03.03 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;GRAFTYS;UNIVERSITE DE NANTES |
发明人 |
BRUNO BUJOLI;CHARLOTTE MELLIER;IBRAHIM KHAIROUN;JEAN-MICHEL BOULER;PASCAL JANVIER;VERENA SCHNITZLER |
分类号 |
C01B25/32;A61L24/00;A61L27/12;A61L27/46;A61L27/58;C04B35/447 |
主分类号 |
C01B25/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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