发明名称 |
POLYVINYLPYRROLIDONE - CHITOSAN IMPLANT FOR ENDOSCOPIC TREATMENT OF VESICOURETERAL REFLUX |
摘要 |
A biocompatible Polyvinylpyrrolidone (PVP)-Chitosan hydrogel implant prepared by gamma radiation crosslinking which can be injected into human body for tissue replacement and augmentation. The implant is prepared by dissolving the PVP and highly deacetylated chitosan in acetic acid solution and irradiating the solution to produce the gel. The synthesized radiation-cross linked PVP-chitosan implant has properties of a good tissue augmenting or bulking substance such as ease of injection through a small gauge needle, stability, biocompatibility and non-migration. PVP-chitosan implant is a potential alternative to the commercially available implant for endoscopic treatment of vesicoureteral reflux (VUR). |
申请公布号 |
PH22014000678(Y1) |
申请公布日期 |
2016.03.28 |
申请号 |
PH22014000678U |
申请日期 |
2014.11.28 |
申请人 |
PHILIPPINE NUCLEAR RESEARCH INSTITUTE (PNRI-DOST) |
发明人 |
LUCILLE V. ABAD, PHD;CARLO C. BISNAR, MD;DAVID T. BOLONG, MD;LORNA S. RELLEVE |
分类号 |
A61K31/722;A61K9/107;A61K31/79;A61L27/20;A61L27/26;A61L27/52;A61L27/58 |
主分类号 |
A61K31/722 |
代理机构 |
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