发明名称 METHOD FOR PRODUCING INSTANT FORMULATION OF FURACILIN (OPTIONAL)
摘要 FIELD: pharmaceuticals.SUBSTANCE: group of inventions is a method for producing instant medicinal forms Furacilin: in the first embodiment, the mixture Furacilin and polyvinylpyrrolidone with a molecular weight of 10,000±2,000 at a ratio of 1:1-3 was dissolved in ethanol 1: 100-300 95±5°C, half of the resulting solution of sodium bicarbonate powder is granulated in a ratio of 1.0:34.0-34.5 Furacilin the total weight, the other half is granulated citric acid powder in a ratio of 1.0 to the total weight of 39.0-39.5 Furacilin , granules mixed 1.00:1.12-1.14 and tableted or packed in sealed packages; second embodiment Furacilin mixture and polyvinylpyrrolidone 1:1-3 were placed in 30-40% ethanol at a ratio of 1:9-12 at 95±5°C, half of the resulting slurry granulated powder of sodium hydrogen carbonate in a ratio of 1.00:2.58-2.60 Furacilin the total weight, the other half is granulated citric acid powder in a ratio of 1.00: 2,96-3,00 by weight Furacilin, granules mixed 1.00:1.05-1.10, tableted or packed in airtight packaging.EFFECT: implementation of the group of inventions and provides a simplification of the application dosage forms Furacilin increases its bioavailability.2 cl, 2 ex, 4 tbl
申请公布号 RU2578456(C1) 申请公布日期 2016.03.27
申请号 RU20140153661 申请日期 2014.12.29
申请人 GOSUDARSTVENNOE BJUDZHETNOE OBRAZOVATELNOE UCHREZHDENIE VYSSHEGO PROFESSIONALNOGO OBRAZOVANIJA PERVYJ MOSKOVSKIJ GOSUDARSTVENNYJ MEDITSINSKIJ UNIVERSITET IM. I.M. SECHENOVA MINISTERSTVA ZDRAVOOKHRANENIJA ROSSIJSKOJ FEDERATSII (GBOU VPO PERVYJ MGMU IM. I.M. SECHENOVA MINZDRAVA ROSSII) 发明人 KRASNJUK IVAN IVANOVICH (ML.);STEPANOVA OLGA IVANOVNA;BELJATSKAJA ANASTASIJA VLADIMIROVNA;KRASNJUK IVAN IVANOVICH;KRASNJUK OLGA VALENTINOVNA;POPKOV VLADIMIR ANDREEVICH;RESHETNJAK VLADIMIR JUREVICH;BAJDIKOVA IRINA VLADIMIROVNA;ENGASHEV SERGEJ VLADIMIROVICH
分类号 A61K31/345;A61K9/16;A61K9/20;A61K9/46;A61K47/32 主分类号 A61K31/345
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