发明名称 METHOD FOR DETERMINING INDIVIDUAL RESPONSIVENESS OF HUMAN MITOCHONDRIA UNDER ACTION OF METABOLIC PREPARATIONS IN TESTS in vitro
摘要 FIELD: medicine.SUBSTANCE: method involves conducting blood analysis and determining a mitochondrial fluorescence both in an initial state, and after adding a blood sample with an examined in vitro metabolic corrector in a dose equal to a recommended single dose, and calculating fluorescence gain rates. If the mitochondrial fluorescence gain rate under the action of the metabolic corrector is >0, the mitochondria are considered activated under the action of the metabolic corrector in a specific patient, whereas the derived gain rate of <0 enables to state the depressed mitochondrial function under the action of the metabolic corrector in a specific patient.EFFECT: presented method enables to determine the patient's individual sensitivity to a specific metabolic corrector for the purpose of the individual selection of a medicinal product and further effective treatment of the patients suffering from ischemic heart disease.1 ex, 5 dwg
申请公布号 RU2578436(C1) 申请公布日期 2016.03.27
申请号 RU20140136064 申请日期 2014.09.04
申请人 FEDERALNOE GOSUDARSTVENNOE AVTONOMNOE OBRAZOVATELNOE UCHREZHDENIE VYSSHEGO PROFESSIONALNOGO OBRAZOVANIYA "BELGORODSKIJ GOSUDARSTVENNYJ NATSIONALNYJ ISSLEDOVATELSKIJ UNIVERSITET" (NIU "BELGU") 发明人 ROMASHCHENKO OLESYA VIKTOROVNA
分类号 G01N33/48 主分类号 G01N33/48
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