发明名称 AGENT WITH ANTITUMOR AND ANTIMETASTATIC ACTIVITY, INCREASING ANTIMETASTATIC EFFECT OF CYCLOPHOSPHAN
摘要 FIELD: pharmaceutics.SUBSTANCE: invention refers to pharmaceutical industry, namely to using liquid alcohol extract of ashberries as an agent showing anticancer, anti-metastatic activity and simultaneously increases anti-metastatic activity of cyclophosphamide. Application of liquid alcohol extract of ashberries (Sorbus aucuparia L.) produced by way of extraction by dynamic fractional maceration milled fruits of mountain ash using acidified ethanol, settling extract, filtering under certain conditions, as an agent showing anticancer, anti-metastatic activity and simultaneously increases anti-metastatic activity of cyclophosphamide.EFFECT: agent described above possesses the manifested antitumour, anti-metastatic activity and effectively improves anti-metastatic activity of cyclophosphamide.1 cl, 1 tbl, 1 ex
申请公布号 RU2578457(C1) 申请公布日期 2016.03.27
申请号 RU20150103700 申请日期 2015.02.04
申请人 FEDERALNOE GOSUDARSTVENNOE BJUDZHETNOE NAUCHNOE UCHREZHDENIE "NAUCHNO-ISSLEDOVATELSKIJ INSTITUT FARMAKOLOGII I REGENERATIVNOJ MEDITSINY IMENI E.D. GOLDBERGA" 发明人 RAZINA TATJANA GEORGIEVNA;ZUEVA ELENA PETROVNA;KALINKINA GALINA ILINICHNA;ISAJKINA NADEZHDA VALENTINOVNA;ANDREEVA VALERIJA JUREVNA;RYBALKINA OLGA JUREVNA;KRYLOVA SVETLANA GENNADEVNA;AMOSOVA EVDOKIJA NAUMOVNA;LOPATINA KSENIJA ALEKSANDROVNA;SAFONOVA ELENA ANDREEVNA;GALIULINA ALINA VALEREVNA
分类号 A61K36/73;A61P35/00 主分类号 A61K36/73
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