摘要 |
FIELD: chemistry.SUBSTANCE: invention relates to the method of producing the compound C:, which includes one- to three-step selective acylation of the hydroxyl group in the first position and in the eleventh position of the compound of formula B1:, with an acylating agent in a solvent selected from N-methyl-2-pyrrolidinone and N,N-dimethylacetamide, in the presence of a base selected from 2,4,6-collidine and 2,6-lutidine, or in the absence of a base.EFFECT: method enables to selectively obtain the compound C with high output.13 cl, 1 dwg, 5 tbl, 25 ex |