TRANSDERMAL PATCH MANUFACTURING METHOD AND TRANSDEMAL PATCH

摘要

A low cost transdermal patch comprises water soluble microneedles and has good performance. A transdermal patch comprises a microneedle sheet, which comprises a plurality of water soluble microneedles, moisture permeable sheet, wherethrough water vapor passes, and a reinforcing film. The reinforcing film is adhered, by an adhesive layer having an adhesive strength less than that of an adhesive layer, onto an outer surface of the moisture permeable sheet, which is the side opposite the skin opposing surface. The reinforcing film includes a water vapor barrier sheet, which blocks the passage of water vapor through at least a first area, and a removable portion around the water vapor barrier sheet. The removable portion is configures such that it can be separated from and peeled off the water vapor barrier sheet.

主权项

1. A transdermal patch manufacturing method comprising:
affixing a water soluble microneedle sheet including a plurality of water soluble microneedles formed in an array in a microneedle sheet affixing process, by affixing the water soluble microneedle sheet in a first area of a moisture permeable sheet capable of passing therethrough water vapor from skin and whereon a first adhesive layer for adhering to the skin is formed on a skin opposing surface side opposing the skin; and assembling the transdermal patch in an assembling process by attaching a reinforcing film, which includes a water vapor barrier sheet, onto an outer surface of the moisture permeable sheet on the side opposite the skin opposing surface using a second adhesive layer, the water vapor barrier sheet blocking the passage of water vapor through at least the first area.