发明名称 DOSAGE REGIMEN FOR A S1P RECEPTOR AGONIST
摘要 S1P receptor modulators or agonists are administered following a dosage regimen whereby during the initial days of treatment the daily dosage is lower than the standard daily dosage.
申请公布号 US2016081949(A1) 申请公布日期 2016.03.24
申请号 US201514956855 申请日期 2015.12.02
申请人 SCHMOUDER Robert;DUMORTIER Thomas;DAVID Olivier;LOOBY Michael 发明人 SCHMOUDER Robert;DUMORTIER Thomas;DAVID Olivier;LOOBY Michael
分类号 A61K31/137 主分类号 A61K31/137
代理机构 代理人
主权项 1. A method of treating an autoimmune disease or disorder in a patient in need of such treatment, comprising administering to said patient an S1P receptor modulator or agonist named 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol in free form or in a pharmaceutically acceptable salt form, or the phosphate thereof of formula IIa, wherein said S1P receptor modulator or agonist is given at a lower than the standard daily dosage of said S1P receptor modulator or agonist during the initial period of treatment and then the dosage is increased, up to the standard daily dosage of said S1P receptor modulator or agonist.
地址 Berkeley Heights NJ US