| 发明名称 |
PROCESS OF PREPARING ALCAFTADINE |
| 摘要 |
The present invention relates to an improved process of preparing substantially pure alcaftadine comprising reacting substantially pure compound of structural formula VIII with more than 20 moles of oxidizing reagent in an organic solvent to obtain alcaftadine:; |
| 申请公布号 |
US2016083389(A1) |
申请公布日期 |
2016.03.24 |
| 申请号 |
US201514944837 |
申请日期 |
2015.11.18 |
| 申请人 |
Enaltec Labs Pvt. Ltd. |
发明人 |
Venkata Sivakumar Bobba;Kodali Eswara Rao;Patel Girish Bansilal;Vaidya Sanjay Dashrath;Tripathi Alok Pramod |
| 分类号 |
C07D487/04 |
主分类号 |
C07D487/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An improved process of preparing an alcaftadine compound of structural formula I comprising the following reaction scheme: wherein the process includes a step of reacting a substantially pure compound of structural formula VIII with more than 20 moles of the oxidizing reagent in an organic solvent to obtain the alcaftadine compound of structural formula I and the substantially pure compound of structural formula VIII is defined as a compound of structural formula VIII having less than 15% of compound of structural formula XIV: |
| 地址 |
Navi Mumbai IN |
