| 发明名称 |
SULFUR DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS |
| 摘要 |
The present invention relates to novel sulfur derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of chemokine receptors. |
| 申请公布号 |
US2016083342(A1) |
申请公布日期 |
2016.03.24 |
| 申请号 |
US201514754493 |
申请日期 |
2015.06.29 |
| 申请人 |
ALLERGAN, INC. |
发明人 |
YUAN HAIQING;BEARD RICHARD L.;LIU XIAOXIA;DONELLO JOHN E.;VISWANATH VEENA;GARST MICHAEL E. |
| 分类号 |
C07C323/67;C07D307/82;C07C317/42;C07D307/64;C07C317/50;C07D213/32;C07D333/34;C07D405/12;C07D233/64 |
主分类号 |
C07C323/67 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A compound having Formula I, its enantiomers, diastereoisomers, hydrates, solvates, crystal forms and individual isomers, tautomers or a pharmaceutically acceptable salt thereof:wherein:
R1 is H; R2 is selected from the group consisting of R5 is —S—, —S(O)—, or —S(O)2—; R6 is selected from the group consisting of R17 is H; R18 is H; R7 is chlorine; R8 is H. |
| 地址 |
IRVINE CA US |
