发明名称 |
PREPARATION METHOD OF 1-PALMITOYL-3-ACETYLGLYCEROL, AND PREPARATION METHOD OF 1-PALMITOYL-2-LINOLEOYL-3-ACETYLGLYCEROL USING SAME |
摘要 |
Disclosed are a method for preparing 1-palmitoyl-3-acetylglycerol in high purity and high yield without a purification process using a column chromatography, and a method for preparing 1-palmitoyl-2-linoleoyl-3-acetylglycerol in high purity and high yield using the same as a key intermediate. The method for preparing 1-palmitoyl-3-acetyl glycerol comprises the steps of: forming a reaction mixture including 1-palmitoyl-3-acetyl glycerol of the Formula 1 in the specification by reacting 1-palmitoylglycerol of the Formula 2 in the specification and an acetylating agent; and separating the optically active 1-palmitoyl-3-acetylglycerol by crystallizing the reaction mixture in a saturated hydrocarbon solvent having 5 to 7 carbon atoms. |
申请公布号 |
US2016083329(A1) |
申请公布日期 |
2016.03.24 |
申请号 |
US201514958734 |
申请日期 |
2015.12.03 |
申请人 |
ENZYCHEM LIFESCIENCES CORPORATION |
发明人 |
LEE Tae-Suk;YOOK Jin-Soo;YOO Chang-Hyun;LEE Cheol-Min;KIM Eun-Kyung;LEE Ju-Cheol |
分类号 |
C07C67/08;C07B57/00;C07C69/30;C07C67/14 |
主分类号 |
C07C67/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Seoul KR |